KMID : 0363120130260040379
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Korean Journal of Pain 2013 Volume.26 No. 4 p.379 ~ p.386
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Intrathecal Meperidine Plus Lidocaine for Prevention of Shivering during Cesarean Section
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Rastegarian Ahmad
Ghobadifar Mohamed Amin Kargar Hossein Mosallanezhad Zahra
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Abstract
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Background: Shivering related to spinal anesthesia may interfere with monitoring and is uncomfortable. The aim of the present study was to investigate low-dose intrathecal meperidine for the prevention of shivering after induction of spinal anesthesia in parturients with cesarean section.
Methods: This was a prospective randomized, double-blind, placebo-controlled trial including 100 parturients, of American Society of Anesthesiologists (ASA) physical status I or II, scheduled for elective cesarean section under spinal anesthesia who were randomly assigned to a meperidine (0.2 mg/kg) plus hyperbaric lidocaine (5%, 75 mg, n = 50; group M) group or a placebo plus hyperbaric lidocaine (5%, 75 mg, n = 50; group L) group. Demographic and surgical data, adverse events, and the mean intensity for each parturient were assessed during the entire study period by a blinded observer.
Results: There were no significant differences between the two study groups regarding the demographic and surgical data (P £¾ 0.05). The incidence of shivering during the entire study period significantly decreased in the group of parturients who received intrathecal meperidine (P = 0.04). There were no significant differences in nausea and vomiting between the two groups.
Conclusions: Low-dose intrathecal meperidine (10 mg) is safe and effective in reducing the incidence and severity of shivering associated with spinal anesthesia in parturients with cesarean section.
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KEYWORD
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cesarean, intrathecal meperidine, shivering, spinal anesthesia
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